he doesn’t know, he doesn't know how to
Il ne sait pas grand-chose de cet animal.
He doesn't know much about this animal.
He doesn't know what it is.
— Harry Potter à l'école des sorciers (2001)
Il ne sait pas ce que c'est d'être pauvre.
He doesn't know what it's like to be poor.
He doesn't know where he is.
He doesn't even know your name.
Il ne sait pas ce que c'est que d'être pauvre.
He doesn't know what it's like to be poor.
Peut-être qu'il ne sait pas quoi faire.
Maybe he doesn't know what to do.
— L'Histoire sans fin (1984)
He doesn't know how to joke.
Il ne sait pas conduire une voiture.
He doesn't know how to drive a car.
Il ne sait pas distinguer le vice de la vertu.
He can't tell vice from virtue.
Il ne sait pas parler anglais et encore moins français.
He doesn't know how to speak English, let alone French.
Il ne sait pas prendre soin de lui-même.
He doesn't know how to take care of himself.
Peu importe comment il essaie, il ne sait pas lire ou écrire.
No matter how hard he tries, he can't read or write.
— Des étoiles sur la terre (2007)
Il ne sait pas jouer en équipe.
He doesn't know how to work as part of a team.