to throw him/it out, to get rid of him/it, to fire him
¡No puedo echarlo, se han fijado en él!
I can't throw him out; they've taken a liking to him!
— Ratatouille (2007)
Podrás echarlo cuando ya no sea valioso y nadie se enterará.
You can throw it away when it's no longer valuable and nobody will know.
— Ratatouille (2007)
Como que el día se niega a irse y hay que echarlo arrastrando.
It's as if the day refuses to leave and you have to drag it away.
— Picnic (1955)
¡Hijo de puta, tienes que echarlo todo a perder!
You son of a bitch, you have to go and ruin everything!
— Хрусталёв, машину! (1999)