his/her wife is
Sa femme est à l'hôpital, elle a été blessée dans un accident de voiture.
His wife is in the hospital; she was injured in a car accident.
Sa femme est sûrement en train de me chercher.
His wife is surely looking for me.
— Les Bonnes étoiles (2022)
Sa femme est originaire de Californie.
His wife is from California.
His wife is Swedish.
Carlos est espagnol et sa femme est allemande.
Carlos is Spanish and his wife is German.
Sa femme est celle qui a été battue à notre arrivée.
His wife was the one who was beaten when we arrived.
— Malèna (2000)
Je crois que la raison pour laquelle il a tué sa femme est toujours un mystère.
I believe the reason why he killed his wife is still a mystery.