彼の妻は

his wife

→ 彼
phrase Uncommon #18,374
his wife は marks the topic of the sentence.
JA: 彼の妻は毎朝コーヒーを飲む。
EN: His wife drinks coffee every morning.

彼の妻はカリフォルニアの出身だ。

His wife is from California.

彼の妻は私には醜いとは思えない。

I don't think his wife is ugly.

彼の妻は、彼が怒った時、彼の扱いを知っている。

His wife knows how to handle him when he gets angry.

彼の妻は彼のためにドアを開けた。

His wife opened the door for him.

彼の妻はもちろん子供たちもそのパーティーに招待された。

His wife, as well as their children, was invited to the party.

彼の妻は私たちのイタリア語の先生だ。

His wife is our Italian teacher.

彼の妻は双子の男の子を産んだ。

His wife gave birth to twin boys.

彼の妻は私の友達のひとりだ。

His wife is one of my friends.

彼は座って雑誌を読み、彼の妻は彼のわきで編み物をしていた。

He sat reading a magazine while his wife knitted beside him.

彼の妻はその事故で死亡した。

His wife died in the accident.

彼の妻は必要から働き出した。

His wife started working out of necessity.