to entrust (something) to him/her, to trust him/her with (something)
Tiene un poco de mala leche, es cierto, pero podrías confiarle a tu abuela.
They’re a bit mean, it’s true, but you could trust your grandmother with them.
— Gángster Americano (2007)
¿A quién podía confiarle el dinero para que les pagara la próxima vez?
Who could I trust with the money so they could pay them next time?
No podemos confiarle algo así a Tom.
We can't entrust something like that to Tom.