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に多大な

a great deal of ... to

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phrase Rare #21,846
a great deal of ... to This is a compositional combination of に, which marks the recipient or affected target, and 多大な, meaning “great” or “substantial.” It is usually followed by a noun such as 貢献 (contribution), 喜び (joy), 損害 (damage), or 影響 (impact).
JA: 彼の発明は社会に多大な影響を与えた。
EN: His invention had a major impact on society.

彼はがんの研究に多大な貢献をした。

He made a significant contribution to cancer research.

彼は姉に多大な愛情を持っていた。

He had a deep affection for his older sister.

嵐は作物に多大な影響を与えた。

The storm had a significant impact on the crops.

その洪水は農作物の収穫に多大な損害を与えた。

The flood caused extensive damage to the crop harvest.

四季の変化は日本の農業に多大な貢献をしている。

The changing seasons make a significant contribution to agriculture in Japan.

その出会いは彼女に多大な喜びをもたらした。

That encounter brought her immense joy.

人々に多大な損害をもたらす犯人は刑務所行きだ

Anyone who causes significant harm to people belongs in prison.

— レベッカ (1940)

その計画を実行に移すのに多大な費用がかかった。

It cost a great deal to put that plan into action.