to give up, to quit
Nunca me ha pasado por la cabeza desistir.
It has never crossed my mind to give up.
O puedes desistir, y dejarlo en adopción.
Or you can give up and put it up for adoption.
— Broker (2022)
No vas a desistir, ¿a que no?
You're not going to give up, are you?
No voy a desistir digas lo que digas.
I won't give up, no matter what you say.
Si están pensando en desistir, háganlo ahora.
If you're thinking of giving up, do it now.
— Máquina de guerra (2026)
No hay vergüenza en desistir.
There is no shame in giving up.