しても無駄だ

it's no use ...

→ 為る
phrase Uncommon #9,603
it's no use ... Follows a verb in the て-form to say that doing something is pointless or won't help.
JA: 彼女に忠告しても無駄だ。
EN: There’s no use advising her.

弁解しても無駄だ。

There's no point in making excuses.

彼女に忠告しても無駄だ。

There's no point in advising her.

彼と論議しても無駄だ。

There's no point arguing with him.

そのことで彼と論議しても無駄だ。

There's no point in arguing with him about it.

彼と議論しようとしても無駄だ。

There’s no point trying to argue with him.

彼らとその問題について議論しても無駄だ。

There's no point in discussing that issue with them.

今更後悔しても無駄だ。

There's no point regretting it now.

彼にそのことを信じさせようとしても無駄だ。

It's no use trying to make him believe that.

大人と口喧嘩しても無駄だよ。

There's no point arguing with an adult.

彼はこの分野でさらに研究しても無駄だと思った。

He thought there was no point in doing any further research in this field.

逃げようとしても無駄だ。

Trying to escape is pointless.

それについて議論しても無駄だ。

There's no point in discussing it.