お二人とも

both of you

→ 御二人
phrase Rare #37,162
both of you A polite way to address two people together; お二人 means “the two of you” and とも means “both.”
JA: お二人とも、こちらへどうぞ。
EN: Both of you, please come this way.

お二人とも独身なんですか

Are you both single?

お二人ともお話がすぐ戻るわ

You two always get back to the topic so quickly.

— ビッグ・シック ぼくたちの大いなる目ざめ (2017)

警察官あっではあのお二人ともご同行あっ

(Police officer) Ah, then, you two, please come with me to the station... (Osamu) Ah!

— 万引き家族 (2018)

お二人とも頑張って

Good luck to both of you.

— 甘い生活 (1960)