qué le pasa

what's wrong with him/her

→ qué

phrase Uncommon #11,979

what's wrong with him/her Used to ask what problem someone has or why they are acting strangely. Can also refer to a thing or situation, depending on context.

SP: ¿Qué le pasa a María? Está muy callada hoy.

EN: What's wrong with María? She's very quiet today.

Anda ¿qué le pasa?

What's wrong with him?

— [REC] (2007)

Qué le pasa, Sra. Lee?

What's wrong, Mrs. Lee?

— Secret Sunshine (2007)

Coronel, ¿qué le pasa?

Colonel, what's wrong?

— Tropa de élite 2 (2010)

Oye, qué le pasa.

Hey, what's wrong with him?

— Wicked (2024)

Por cierto, ¿qué le pasa?

By the way, what's wrong with him?