radically, completely, dramatically
Cambió radicalmente de postura.
He radically changed his stance.
Nuestra vida cambió radicalmente.
Our lives changed radically.
En los últimos treinta meses muchas cosas han cambiado radicalmente.
In the last thirty months, many things have changed radically.
Tom cambió radicalmente de postura.
Tom radically changed his stance.
La trayectoria vital de Mary ha cambiado radicalmente desde entonces.
Mary's life path has changed radically since then.