full-scale, full-fledged, serious, authentic
本格的な結界が張ってある
A powerful barrier has been set up.
— 崖の上のポニョ (2008)
失礼ですがかつてあなたは本格的な作家?
If you don't mind my asking, were you once a professional writer?
— 甘い生活 (1960)
それから本格的な掃除を始めた。
Then I started cleaning in earnest.
本格的に雨が降り出した。
The rain really started coming down.