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彼の手紙に返事を

a reply to his letter

→ 彼
phrase Rare #37,134
a reply to his letter This phrase is an object phrase ending with を and is usually followed by a verb such as 書く (write) or 出す (send).
JA: 彼の手紙に返事を書きました。
EN: I wrote a reply to his letter.

彼の手紙に返事を出すことを忘れるな。

Don't forget to reply to his letter.

私は彼の手紙に返事を出したくない。

I don't want to reply to his letter.

忘れずに彼の手紙に返事を書くんだよ。

Don't forget to reply to his letter.

私はさっさと彼の手紙に返事を書いてしまうつもりだ。

I intend to write back to his letter right away.