些細なことで

over trivial things

→ 些細だ
phrase Rare #29,069
over trivial things Used when something happens because of, or in response to, a minor or insignificant matter. 些細なこと means “a trivial matter,” and で marks the cause or circumstance.
JA: そんな些細なことで怒らないで。
EN: Don't get angry over such a trivial thing.

彼女はいつも些細なことで悩んでいる

She is always worrying about trivial things.

些細なことで

Even the smallest things.

— ミスティック・リバー (2003)

彼は些細なことで腹を立てる

He gets angry over trivial things.

こんな些細なことでガタガタ文句言うな

Don't make such a fuss over something so trivial.