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に手を触れるな

don't touch

→ に
phrase Rare #38,843
don't touch A blunt prohibition. The particle に marks the person or thing not to touch; 手を触れる literally means “touch with one’s hand.”
JA: 展示品に手を触れるな。
EN: Don't touch the exhibits.

彼に手を触れるなと―中尉が命令したなら―なぜ転属を？

If the lieutenant ordered us not to lay a hand on him, then why the transfer?

— ア・フュー・グッドメン (1992)

その男に手を触れるな

Don't lay a hand on that man.

— The Wind Rises (2013)