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に別れを告げ

say goodbye to

→ に
phrase Rare #20,664
say goodbye to The に marks the person or people being addressed. Often sounds somewhat formal or literary; the phrase can also imply leaving someone or somewhere behind.
JA: 友達に別れを告げて、駅へ向かった。
EN: I said goodbye to my friends and headed to the station.

彼に別れを告げ、彼女は家を出た。

She said goodbye to him and left the house.

彼は家族に別れを告げ、ニューヨーク行きの飛行機に搭乗した。

He said goodbye to his family and boarded a plane bound for New York.