IndianUsually means from India when describing a person or thing. When referring to Indigenous peoples of the Americas, the word can be outdated or offensive; use a more specific term when possible.
Indigenous person, Native AmericanCan be considered offensive or outdated when used for Indigenous people; prefer a specific people’s name or an appropriate term such as “Indigenous person.”
SP: El indio vive cerca del río.
EN: The Indigenous man lives near the river.
IndianCan also refer to a person from India, though “persona de la India” is clearer and avoids ambiguity.