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薬の効果は

the medicine's effects

→ 薬
phrase Rare #41,605
the medicine's effects 薬の効果 means “the effect of the medicine,” and は marks it as the topic. This phrase usually comes at the beginning of a sentence and is followed by a description of the effects.
JA: この薬の効果はすぐに現れます。
EN: This medicine's effects appear quickly.

薬の効果はわずか

The medicine's effect is minimal.

— カンフーハッスル (2004)

その薬の効果は強烈だが短い。

The effects of that drug are powerful but short-lived.

幸い、薬の効果はすぐに現れた。

Fortunately, the medicine took effect right away.