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愛想がつきた

I've had it with

→ 愛想
phrase Rare #34,600
I've had it with An idiomatic expression for becoming completely fed up with or losing patience with someone or something.
JA: 彼の言い訳には愛想がつきた。
EN: I've had it with his excuses.

人間というものに愛想がつきたのです

I've lost faith in humanity.

君には愛想がつきたよ。

I've had enough of you.

てめえ達にゃ愛想がつきたぜ

I’ve had it with you lot.

— Sanjuro (1962)