の変化に

to changes in

→ の
phrase Rare #42,153
to changes in Used when describing a response, adaptation, or reaction to changes in something. The particle に can also be followed by compounds such as に対して or も.
JA: 季節の変化に体が慣れるまで時間がかかります。
EN: It takes time for the body to get used to changes in the seasons.

体は温度の変化にすばやく順応する

The body quickly adapts to changes in temperature.

どんな状況の変化に私に知らせてください

Please notify me of any changes in the situation.

私はこんな流行の変化についていけない

I can't keep up with changes in trends like this.