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お変わり

change

→ 御変わり
お honorific/polite prefix + 変わり change, become different
noun Rare #42,569
change Polite, honorific form, often used when asking about someone’s condition or appearance, as in お変わりありませんか (How have you been?).
JA: お変わりありませんか。
EN: How have you been?

体調は以前とお変わりありませんか？

How have you been feeling lately?

あなたは少しもお変わりになっていませんねあの時のまま

You haven't changed at all—you’re just as you were back then.

— The Wind Rises (2013)