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sua moglie e i suoi figli

his wife and his children

→ suo
phrase Rare #46,845
his wife and his children The possessives agree with the nouns; sua and suoi can refer to his or her, depending on context.
IT: Marco ama sua moglie e i suoi figli.
EN: Marco loves his wife and his children.

Lui ha abbandonato sua moglie e i suoi figli.

He abandoned his wife and children.

Sami uccise sua moglie e i suoi figli.

Sami killed his wife and children.

A Sami mancavano sua moglie e i suoi figli.

Sami missed his wife and children.

Sami ha ucciso sua moglie e i suoi figli.

Sami killed his wife and children.