Le interesa

is interested in

→ le
phrase Rare #51,890
is interested in Le can refer to him, her, or you (formal). The thing that interests the person is the grammatical subject.
SP: ¿Le interesa la música?
EN: Are you interested in music?

¿Le interesa la pintura?

Are you interested in painting?

— Русский ковчег (2002)

¿Le interesa?

Are you interested?

— Atlantis: El imperio perdido (2001)

¿Le interesa el arte?

Are you interested in art?

¿Le interesa el idioma bereber?

Are you interested in the Berber language?