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я ничего не понимаю в

I don't understand anything about

→ я
phrase Rare #38,897
I don't understand anything about Followed by a topic; the noun after «в» is in the prepositional case.
RU: Я ничего не понимаю в шахматах.
EN: I don't understand anything about chess.

Я ничего не понимаю в классической музыке.

I don't know anything about classical music.

Я ничего не понимаю в науке.

I don't understand anything about science.